Oksana kehoe biography
Biography
Dr Oksana Kehoe is a Senior Lecturer in Inflammation Biology at the School of Medicine and Lead of Rheumatology Research laboratory in the Robert Jones & Agnes Hunt Orthopaedic Hospital at Oswestry.
Dr Kehoe completed her PhD in the RE Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of National Academy of Sciences of Ukraine, Kyiv where she was awarded a Fellowship of Ukrainian Government for young scientist.
Her academic career started in Ukraine, where she worked as a Research Scientist in the Department of Biochemistry, Taras Shevchenko National University of Kyiv, Ukraine. After moving to the UK in , Dr Kehoe worked as a Postdoctoral Research Associate at Cardiff University () and the University of Manchester (). She joined Keele University and Institute for Science & Technology in Medicine at the RJAH Orthopaedic Hospital as a Research Fellow in In , Dr Kehoe was appointed as a Lecturer in Bioscience at the School of Medicine and promoted to a Senior Lecturer in
Further information
The Rheumatology Research lab is based at the RJAH Orthopaedic Hospital, Oswestry as part of the FMHS Regenerative Medicine theme. The combined clinical and research excellence in Oswestry has contributed extensively to the current knowledge of mechanisms and therapy treatments for arthritis.
Rheumatology Research laboratory at the RJAH Orthopaedic Hospital, Oswestry
Present PhD students:
- Mairead Hyland funded by Keele ACORN, Rheumatology Trust Fund and Institute of Orthopaedics, Oswestry; Project ‘Mesenchymal stem cell-derived extracellular vesicles as therapeutic agents in arthritis’.
- Rebecca Davies EPSRC/MRC Centre for Doctoral Training in Regenerative Medicine; Project ‘Determining the role of microRNAs in extracellular vesicles produced by hypoxia-preconditioned mesenchymal stem cells in inflammation’ (collaboration with Dr Mark Platt, Loughborough University).
- Anais Mako
- Dr Oksana Kehoe. Lead
Our expertise
Teaching staff
Research within the School bridges the interface between new advances in science and technology with medicine and clinical practice, bringing together biological scientists, physicists, chemists, engineers, mathematicians and clinicians. Our exceptional track record in bench and bedside regenerative medicine research builds on the reputation and success of the former Institute for Science and Technology in Medicine (ISTM) which has now integrated within the School.
Our course taps expertise from a variety of internal and external academics, renowned in their particular areas of research, to deliver teaching on a range of topics for core and elective modules, providing flexibility in the breadth of topics you can choose to study via optional modules. You’ll have access to hear from guest lecturers about current developments in the field of stem cell technology and bioengineering. Recent external speakers have included Professor Sian Harding (Cardiac regenerative Medicine at Imperial College London), Professor Sarah Cartmell (Biomaterials at the University of Manchester), Professor Aldo Bocaccini (Tissue engineering at FA University, Erlargen, Nuremberg).
Teaching team includes:
Dr Vinoj George, Course Director and Lecturer – His research interest is in understanding and modulating mechanisms associated with cardiovascular cell biology and cardiovascular diseases, with the aid of genome engineering in human Induced Pluripotent Stem Cells (hiPSCs).
Dr Nicholas Wragg, Lecturer in Bioengineering – His research is focused on complementary areas of regenerative medicine: Musculoskeletal Tissue Engineering, and Regenerative Medicine Biomanufacturing and Process Development.
Professor Ying Yang, Professor in Biomaterials and Tissue Engineering – Ying's current research has been focused on the application of engineering strategies in translational medicine. This includes smart nanofiber design and
RESEARCH OVERVIEW
Our Research Panel, along with stringent peer review, approve projects for funding. The range of research is impressive, from clinical trials in common orthopaedic problems to molecular biology approaches to less common forms of muscular dystrophy and gait analysis in children with cerebral palsy. All well designed studies on conditions affecting patients attending our hospital.
An example of the Institute working closely with the RJAH Hospital to take forward important initiatives includes the OsCell Cell Therapy Unit.
We continue to provide funding for the Oscell Cell Tharapy Unit, as we have done for more than twenty years in order to provide cells for clinical trials into repair of damaged joint cartilage.
The ASCOT Study looked at Autologous Chondrocyte Implantation (ACI), a technique used to help patients with an articular cartilage defect, something that can impact younger people in their 20s and 30s.
The procedure sees a sample of cartilage removed from the patient’s knee from which their own cells are then grown in a laboratory.
The National Institute for Health and Care Excellence (NICE) concluded the evidence to be enough to approve the technique for wider use on the NHS. We were the first site in the UK licenced to offer ACI.
Read more about Cell Therapies
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